“Contrast agents are much less nephrotoxic than previously thought”, said Aart van der the current ESUR Contrast Media Safety Committee (CMSC) guideline. Renal adverse reactions to gadolinium-based contrast agents B How long should there be between two iodine-based contrast media injections for routine. The Contrast Media Safety Committee of the European Society of Urogenital Radiology is proud to present the 10th version of its Contrast Agent Guidelines.

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Symptomatic and similar to the management of other drug-induced skin reactions versin. Iodine-based contrast medium Correlation of time of the contrast medium injection with the hemodialysis session is unnecessary. Supportive treatment including observation. Consider an alternative imaging method not using iodine-based contrast media. Late skin reactions of the type which occur after iodine-based contrast media have not been described after gadolinium-based and ultrasound contrast media.

Reducing the risk of iodine-based and MRI contrast media administration: Drug prophylaxis is generally not recommended. Dialysis and contrast medium administration Medis. Intra-arterial contrast medium administration with first pass renal exposure. Hypotensive shock Respiratory arrest Cardiac arrest Convulsion.

See renal adverse reactions see 2. Oral hydration alone is not recommended.

However, there is no evidence that hemodialysis protects patients with impaired renal function from contrast medium induced nephropathy or nephrogenic systemic fibrosis.

Type and severity of reactions. Gadolinium-based contrast medium Hemodialysis to remove the contrast medium is unnecessary for iodine-based contrast medium, but for gadolinium- based contrast medium. Maculopapular rashes, erythema, swelling and pruritus guidlines most common. Emdia reports from international congresses Hundreds of summaries from the leading radiology journals Videos and interviews with radiologists from all over the world.


In this case, three precautionary steps should be followed: Consider the use of premedication. Intravenous cholangiographic contrast media should not be given to patients at risk. Use a different iodine-based agent for previous reactors to contrast medium. Breast feeding should be avoided for 24 hours after contrast ugidelines if high risk agents are used. Never deny a patient a clinically well- indicated enhanced MRI examination.

Stages 2 and 3 rarely apply in the radiology setting. Measurement of renal function B.

Consider an alternative test not requiring an iodine-based contrast agent. In which patients should serum-creatinine be measured before contrast medium administration? For chest and brain examinations, either CT or MR may be done first. An adverse reaction which occurs within 1 hour of contrast medium injection.

ESUR Guidelines

Do not perform non-emergency biochemical analysis of blood and urine collected in the 24 hours after contrast medium injection. Gadolinium- containing contrast media for radiographic examinations: Effect of iodinated contrast media on thyroid function in adults.

No pharmacological prophylaxis with renal vasodilators, versjon antagonists of endogenous vasoactive mediators or cytoprotective drugs has yet been shown to offer consistent protection against contrast induced nephropathy. Although the contrast agents in guidepines use have been on the market for many years, minor changes occur in their adverse reaction pattern and new observations are reported.


Test injection with normal saline. We hope that you find our guidelines very helpful in your daily practice.

ESUR Guidelines :

Following administration of gadolinium-based agents to the mother during pregnancy, no neonatal tests are necessary. Renal adverse reactions to gadolinium-based contrast agents. Use non-ionic iodine-based contrast medium.

Powered By T3 Framework. Bone, red blood cell labelling. Please send me the monthly newsletter. Since our first guidelines were published, more than No other contrast medium guidelines have been printed in such numbers or so many languages. Renal adverse reactions to iodine-based contrast media. Refer to renal adverse reactions section 2. Multiple myeloma patients B.

Most skin reactions are mild to moderate and self-limiting. Patients with diabetes mellitus taking metformin B. This differentiation is important for patient stratification: Iodine-based contrast medium Hemodialysis to remove the contrast medium is unnecessary.

To reduce any potential for nephrotoxicity the following are recommended: Versoon adverse reactions B. Neither serum nor plasma creatinine is an ideal indicator of renal function and may miss decreased renal function.