Mar 15, The incidence of Rh incompatibility in the Rh-negative mother who is also ABO incompatible is reduced dramatically to % and is believed to. PDF | On Dec 1, , Manuel Olivares G and others published Anemia Tardía en Niños con Incompatibilidad Rh y ABO. Download Citation on ResearchGate | Enfermedad hemolítica del recién nacido por incompatibilidad ABO | The hemolytic disease of the newborn due to ABO.

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The above will provide information which would support national programs for blood and organ transplant in Mexico as well as increase the knowledge of Mexican genetics.

Blood Groups Distribution and Gene Diversity of the ABO and Rh (D) Loci in the Mexican Population

Esta mayor cantidad de anticuerpos puede poner en peligro la vida de un feto en el futuro. According to these observations, populations were analyzed to know if they were in the Hardy-Weinberg equilibrium HWE. A geographic clustering in these groups was not evident Figure 3. Additionally, these works have explored the possible effects of the genetic content in the clinic context [ 19 ]. View at Google Scholar G. The above would be possible by the lowest heterozygosity found in Puebla in which the highest frequencies of the and alleles were observed.

Together these works show the effects of gene diversity on diagnostic tools and the risk to get some diseases that will have to be taken into account in the future to improve accuracy in biomedicine.

Women’s Health Care Physicians

More than a century has passed since the discovery of ABO system by Karl Landsteiner in ; this knowledge has contributed to the understanding of some mechanisms basis of heredity, and today it still has a great conceptual and clinical interest [ 1 ]; also, blood antigens had been related to predisposing individuals to some diseases like cancer, diabetes, infectious diseases, and heart illnesses [ 2 — 4 ] or protecting individuals against some diseases such as malaria and diabetes [ 56 ].


For example, in Mexico, some works have found a positive association between specific HLA haplotypes and acute kidney rejection [ 1517 ]. Se puede administrar tratamiento para evitar estos problemas. What’s Normal Prenatal Tests: Similarly, for the D locus in SinaloaSonoraand Durango the highest heterozygosities were observed, while the lowest heterozygosities were observed in PueblaSan Luis Potosiand Estado de Mexico Table 3.

El Factor Rh

This information will allow health abp to obtain enough blood units since the site where it is more frequent to get a specific blood type with the confidence that these frequencies will be relatively constant is known, and it will be not necessary to investigate the distribution of blood groups in these populations again as soon. For the above, it is necessary to implement effective programs among health incompagibilidad to get specific blood types and products according to their geographic distribution.

View at Google Scholar R. Different factors like migrations, nonrandom mating, and infectious diseases among others would confer evolutionary constraints over this genetic trait [ 44344 ]; it would be possible that both loci have some selection pressure resulting in their current distribution in Mexico; however, this remains unexplored yet.

For this study, samples were obtained from metropolitan cities, most of which are composed of mestizo individuals; variability in proportions of blood antigens was found in different areas of the country.

Women’s Health Care Physicians. PC1 and PC2 explain Additionally, we used the ABO and D loci as a genetic trait to investigate gene structure of Mexican populations. The PC1 differentiates populations with high frequencies of, and alleles; meanwhile, PC2 separates those with high proportions of and alleles; according to this, four groups could be defined Figure 3.

For specific medical advice, diagnoses, and treatment, consult your doctor. This stabilizes the level of red blood cells and minimizes damage from Rh antibodies already in the baby’s bloodstream.

Hillyer, American Association of Blood Banks: Likewise, it will contribute to the study of Mexican genetics by showing its differentiation among the country, which could have important implications in different fields of biomedicine such as transplant medicine and immunology, as well as the treatment and diagnosis of several pathologies present in the country.


A total ofindividuals from 17 states of Mexico were studied between the years and El feto puede heredar el factor Rh del padre o de la madre. Blood groups were tested insubjects from to It would be interesting to investigate the reason for the reduction in heterozygosity of both loci in Puebla. In the second; Sinaloa, Sonora, Jalisco, Michoacan, Nayarit, Baja California, and Durango were included which have higher frequencies of the and alleles in the case of Durango. This can make the baby’s red blood cells swell and rupture.

ElFactor Rh: Las Causas, el Tratamiento y la Prevención

Erythrocytes were separated for the determination of blood type. The selection of participants was performed aabo a nonprobabilistic sampling with information on the blood group test. The frequency observed was slightly similar to those found in indigenous populations [ 37 — 39 ], reflecting the complex processes of the admixture giving rise to Mexican mestizo populations [ 9 ].

The above could be explained by the sampling method used, which would result in the overrepresentation of females in the sample. National average of blood group: It would be interesting to analyze if there is any influence of gene diversity in clinical traits. Cruz-Zamudio3 Tania G.

Rh antibodies are harmless until the mother’s second or later pregnancies. The main challenge is to understand how to promote tolerant immune responses against allograft tissues; different factors such as age, viral serology, and gender had been studied to identify their relationship with allograft rejection.